Small Molecule Chemical Probes

 The Koehler Lab has developed small molecule probes of proteins involved in various cellular pathways. For each probe listed below, 'target' links provide information about the development of the probe against the target and 'probe' links provide information about the small molecule probe, including commercial sources for acquiring the probe for your research purposes.

To learn more about chemical probes within the wider research community, please visit chemicalprobes.org

 


 
Orai1_AnCoA4.png
 

Target:  Orai1

Probe:  AnCoA4

 


 
 

Target:  Amyloid-β

Probe:  2002-H20

 

 
hedgehog_Robotnikinin.png
 
 

 
 

Target:  SR-BI

Probe:  BLT-1

 

 
calmodulin_Calmoduphilin.png
 

Target:  Calmodulin

Probe:  Calmoduphilin

 

 
 

Target:  Hap3p

Probe:  Haptamide B

 



 
pde3a_DNMDP.png