Small Molecule Chemical Probes

 The Koehler Lab has developed small molecule probes of proteins involved in various cellular pathways. For each probe listed below, 'target' links provide information about the development of the probe against the target and 'probe' links provide information about the small molecule probe, including commercial sources for acquiring the probe for your research purposes.

To learn more about chemical probes within the wider research community, please visit



Target:  Orai1

Probe:  AnCoA4



Target:  Amyloid-β

Probe:  2002-H20




Target:  SR-BI

Probe:  BLT-1



Target:  Calmodulin

Probe:  Calmoduphilin



Target:  Hap3p

Probe:  Haptamide B